Respiratory depression and partial airway obstruction, especially when combined with narcotics or in patients with hypercarbic respiratory disease.Reassess dose Q12 H and wean to lowest dose required to achieve sedation targetġ00 mg/50 mL dextrose 5% or sodium chloride 0.9% for syringe pump infusion.Dosage reductions recommended in patients with CHF, septic shock, renal and/or hepatic dysfunction, low serum albumin, pulmonary insufficiency, COPD, or elderly patients.Initiate at 1 - 5 mg/hr titrate to individual response and to target VAMAAS (tolerance may occur). Reduce the dose by 30% in patients premedicated with narcotics and CNS depressants muscle relaxant - useful in patient with tetanus.useful in the management of alcohol withdrawal and delirium tremens.has no long-term anticonvulsant activity.used in the initial control of seizures or in the treatment of status epilepticus.
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